Description
GHRP-6 & CJC-1295 Mix
5mg ghrp-6 & 5mg cjc-1295 in each vial
Description
GHRP-6 (Growth Hormone Releasing Peptide —6) is a hexapeptide with a chain
composed of 6 amino acids. It is one of several synthetic met-enkephalin analogs
that include unnatural D-amino acids that were developed for their growth hormone
releasing activity and are called growth hormone secretagogues. GHRP-6 is true
HGH secretagogue.
This growth hormone releasing peptide is distinct from GHRH and do not act at the
GHRH receptor, but instead acts al the growth hormone secretagogue receptor, now
renamed as the ghrelin receptor.
CJC-1295 is a tetrasubstituted 30-amino acid peptide hormone, primarily
functioning as a growth hormone releasing hormone (GHRH) analog. It has D-Ala,
Gin, Ala, and Leu substitutions at positions 2, 8, 15, and 27 respectively.
GHRP-6 & CJC-1295 are sterile, non-pyrogenic, white lyophilized powder intended
for subcutaneous or intramuscular injection, after reconstitution with sterile Water
for Injection.
Mechanism of Action
GHRP-6 is not an active fragment of growth hormone releasing hormone (GHRH).
Which means it stimulates the body’s own secretion of HGH. Human Growth
hormone has been shown in studies to promote lean body mass and reduce
adiposity (fat). This growth hormone releasing peptide is distinct from GHRH and do
not act the GHRH receptor, but instead acts al the growth hormone secretagogue
receptor, now renamed as the gh-relin receptor.
GHRP-6’s special sequence is considered to provide a signal to the body to begin
secreting Growth Hormone (GH) release while also blocking Somatostatin, a
hormone that inhibits Growth Hormone release. Research Studies have shown that
GHRP-6 stimulation of Growth Hormone has host of beneficial effects such as
decreased body fat, increased muscle, and increased strength and stamina so
maximizing the production and secretion can be great addition to improved animal
physical shape. Increased amounts of Growth Hormone then can cause the liver to
secrete the hormone IGF-1 which has also been implicated in improving the animal
body’s ability to burn fat and build muscle. Clinical cases have shown that the use of
GHRP-6 was associated with increased muscle mass and a reduction of body fat.
GHRP-6 has been one of the most thoroughly studied and is believed to be acting
naturally on both pituitary and hypothalamic sites (Fairhall et al, 1995). This has
been demonstrated in the primary pituitary cells of rats in a time-dependent and
dose-dependent manner. In another study of Fairhall et al. (1995), they concluded
that the major target of the GHRP-6 in vivo is the hypothalamus after observing that
the GH(Growth Hormone) release induced by the central GHRP-6 administration is
guinea pigs was inhibited by the central action of somatostatin. Furthermore, an
inhibition by somatostatin with the activated GRF neurons (GRF=Growth Hormone
Releasing Factor), induced by GHRP-6, was observed via receptors known to be
located on or near the GRF themselves. However, it was also observed that GHRP-6
had no effect on the intracellular cAMP levels unlike that of GHRP-2. This particular
experiment further indicated that GHRP-6 is effectively stimulating GH release from
somatotrophs through different receptors, the mechanisms of which are not yet
known (Chan et al. 1989).
However, some researchers suggest that action and efficiency of growth hormone is
dependent on the physical condition of the experimental unit. In humans for
example, GH secretion decreased with obesity. This is contrary in the case of the
GHRP-6 which showed increased (almost twice that of GHRP) GH responses when
administered in obese patients (Cordido et al. 1993). Though obesity has shown
affecting the efficiency of the hormone, it was also suggested that GHRP-6’s effects,
at least at the dose-dependent manners, were found to be sex-and age-independent
without being affected by the adrenergic pathways using the a2 adrenergic
receptors (Penalva et al. 2008).
CJC-1295 is a long acting growth hormone releasing hormone (GHRH) analog.
GHRH, also known as growth hormone releasing factor or somatocrinin, which is
produced by the arcuate nucleus in the hypothalamus. It stimulates secretion of
growth hormone from the pituitary gland and is released in a pulsatile manner to
ultimately stimulate pulsatile release of growth hormone. The result is an increasing
level of both HGH (Human Growth Hormone) and IGF-1 (Insulin-like Growth
Factor).
One very important advantage of CJC-1295 is that because of its half life, which is
between 10-30 minutes, the user can control the levels of HGH and IGF-1. That
means you can have high levels, when you think its best for results.
The possible benefits of GHRP-6/CJC-1295 combination:
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- Fat loss
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- Better sleep
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- Muscle gain
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- More energy
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- Increased strength
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- Stronger bones
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- Improved skin tone
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- Connective tissues
Adverse reactions
Both GHRP-6 and CJC-1295 are generally very well tolerated by most individuals
when used at the recommended dosages of about 100mcg per injection.
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- Water Retention
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- Head “rush” immediately after the injection
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- Tiredness
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- Increased Hunger
Instructions for reconstitution
Flip off the top of the peptide vial with your thumb. Use the alcohol swab to wipe the
rubber stopper of the peptide vial. Push the needle of the syringe into the middle of the
rubber stopper so it goes through the rubber and into the vial. Now, while angling the
needle so that the water for injection goes down the side of the glass, rather than
directly into the powder, inject the water for injection into the vial. Repeat this step until
you have the correct amount of water in the vial. The powder will dissolve quickly,
however it can help to gently roll the vial in between your fingers (do not shake the vial
vigorously). Remove the syringe and dispose of it. You should never reuse a syringe.
Dosage
Recommended dosage for mixture of GHRP-6 & CJC-1295:
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- 200mcg (0.10mg) once per day for anti-aging.
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- Between 800-1200 mcgs, divided in two or three doses per day for
muscle gain and fat loss, directed via subcutaneous injections.
Storage
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- After reconstitution, may be stored for a maximum of 14 days in a refrigerator at 2°C — 8°C.
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- Store vials in an upright position.
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- Store in a refrigerator (2°C — 8°C). Keep in the outer carton in order to protect from light.
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- For one month can be stored at room temperature.
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